執(zhí)照.jpg)
黃芩素
分析標準品,HPLC≥98%
Baicalein
CAS號：491-67-8
分子式：C15H10O5
分子量：270.24
MDL：MFCD00017459
貨號 | 規(guī)格/參數(shù)/品牌 | 價格 | 貨期 |
YJ-B20571-20mg | 分析標準品,HPLC≥98% | ￥190.00 | 現(xiàn)貨 |
YJ-B20571-100mg | 分析標準品,HPLC≥98% | ￥550.00 | 現(xiàn)貨 |
YJ-B20571-500mg | 分析標準品,HPLC≥98% | ￥1300.00 | 現(xiàn)貨 |
JS25956-1g | ≥98% | ￥338.00 | 現(xiàn)貨 |
JS25956-5g | ≥98% | ￥488.00 | 現(xiàn)貨 |
JS25956-25g | ≥98% | ￥1164.00 | 現(xiàn)貨 |
JS25956-100g | ≥98% | ￥2980.00 | 現(xiàn)貨 |
A10092-20mg | 分析標準品,含量94.1%，可溯源 | ￥300.00 | 現(xiàn)貨 |
JT92305-1ml買5贈1 | 10mM in DMSO | ￥577.00 | 現(xiàn)貨 |
產(chǎn)品介紹
Baicalein (5,6,7-Trihydroxyflavone) 是黃嘌呤氧化酶抑制劑，其 IC50 值為 3.12 μM。
熔點：256-271℃
沸點：575.9℃ at 760 mmHg
比旋光度：-139°(吡啶)
外觀：黃色粉末
溶解性：DMSO : 50 mg/mL (185.02 mM; Need ultrasonic)，DMSO母液分裝保存，不能反復凍融，-20℃，一個月內(nèi)使用，-80℃，半年內(nèi)使用。
敏感性：對光和熱敏感
儲存條件：2-8℃
注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。
參考文獻(141篇)
141. [IF=2.5] Yingmei Lai et al."Ginsenoside Rb1/baicalein nanoparticles: a potential nanomedicine for toxoplasmosis therapy."ACTA TROPICA.2025 Jul;:107740
140. [IF=4.8] Weiguang Lv et al."Baicalein ameliorates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and regulating gut microbiota."Frontiers in Pharmacology.2025 Jul;16:
139. [IF=8.3] Liqun Jia et al."Wuse-oil Compound 03 Mitigates Radiation-Induced Oral Mucositis by Modulating Oral Microbiota to Mediate TLR4/NF-κB Pathway and Inhibit M1 Macrophage Polarization."PHYTOMEDICINE.2025 Jul;:157083
138. [IF=4.8] Wei Wang et al."Baicalein from Scutellaria baicalensis mitigates oxidative stress through the IIS pathway in a C. elegans model of ulcerative colitis."Frontiers in Pharmacology.2025 Jun;16:
137. [IF=5.7] Huang Zhiqi et al."Sanhuang Xiexin Decoction ameliorates lipid disorders in obese mice via inducing browning of white adipose tissue and activating brown adipose tissue."Chinese Medicine.2025 Dec;20(1):1-17
136. [IF=5.9] Ping Lin et al."Impact of filtration processes on the key chemical components of Shanxi aged vinegar."Food Bioscience.2025 Jul;69:106827
135. [IF=13.2] Cong Cheng et al."Hierarchical all-carbon nanozyme architectures for enhanced intelligent rutin detection."CHEMICAL ENGINEERING JOURNAL.2025 Jun;514:163289
134. [IF=4.1] Jinquan Zhang et al."Multi-Target Synergy Against Acute Lung Injury: Systems Pharmacology Decoding Dahuang-Huangqin Herb Pair’s Therapeutic Mechanism."Journal of Inflammation Research.
133. [IF=2.6] Yinzi Yue et al."Synergistic mechanisms of Banxia Xiexin decoction in overcoming chemoresistance and enhancing chemosensitivity in colorectal cancer."FITOTERAPIA.2025 Sep;185:106711
132. [IF=4.8] Liansheng Qiao et al."Scutellaria baicalensis ameliorates allergic airway inflammation through agonism and transcriptional regulation of TAS2Rs."JOURNAL OF ETHNOPHARMACOLOGY.2025 Jan;337:118881
131. [IF=2.7] Dan-ni Chen et al."Promotion of a quality standard for Scutellariae radix based on the anti-inflammatory efficacy-oriented quality marker of the effect-constituent index."Analytical Methods.2024 Nov;:
130. [IF=3.2] Haonan Zhang et al."A comprehensive profiling of phenolic compounds and antioxidant activities of 24 varieties of red raspberry cultivated in Northeast China."JOURNAL OF FOOD SCIENCE.2024 Dec;90(1):e17623
129. [IF=5.6] Shuyun Zhu et al."Fluorescent distinguishing flavonoid glycosides against aglycones based on the selective recognization of boric acid-functional Eu(III)-organic framework."TALANTA.2025 May;286:127559
128. [IF=2.9] Dan Song et al."The Mechanism of Baicalin in the Treatment of Mycoplasma Pneumoniae Pneumonia by Regulating NLRP3/Caspase-1 Signaling Pathway."IMMUNOLOGICAL INVESTIGATIONS.
127. [IF=2.6] Zengfa Wang et al."Baicalein antagonises Rhopilema esculentum toxin-induced oxidative stress and apoptosis by modulating ROS-MAPK-NF-κB and inhibiting PLA2 activity."TOXICON.2025 Jan;:108266
126. [IF=2.5] Juncheng Li et al."Study on the Molecular Mechanism of Baicalin Phosphorylation of Tau Protein Content in a Cell Model of Intervention Cognitive Impairment."Neuropsychiatric Disease and Treatment.
125. [IF=4.9] Xin Zuo et al."Functional Characterization of β-Glucuronidase Genes Involved in Baicalein Biosynthesis from Scutellaria baicalensis Based on Transcriptome Analysis."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2025 Jan;26(5):1793
124. [IF=5.3] Wanbing Pan et al."Baicalein nanoemulsion in situ GEL for dry age-related macular degeneration."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2025 Mar;:125494
123. [IF=5.6] Hao Guo et al."Research on the synergistic optimization of Scutellaria baicalensis yield, quality and soil environment by key microorganisms, driven by the combined approach of reducing chemical fertilizer usage while incorporating organic fertilizer."IND
122. [IF=8.5] Shengnan Wang et al."Postharvest changes in the phenolic and free volatile compound contents in Shine Muscat grapes at room temperature."FOOD CHEMISTRY.2025 Feb;465:141958
121. [IF=2.6] Guo Huihui et al."Deacidification characteristics of Issatchenkia terricola WJL-G4 with a special focus on bioactive compounds and antioxidant activities during currant juice and wine processing."INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY.2025 J
120. [IF=3.8] Chun Chen et al."Cell-free synthesis of membrane receptors for preparation of NKG2A monolithic micro-affinity chromatography."JOURNAL OF CHROMATOGRAPHY A.2025 Apr;1746:465775
119. [IF=3.9] Riying Deng et al."Baicalein inhibits Micropterus salmoides rhabdovirus replication in vitro and in vivo."AQUACULTURE.2025 May;601:742309
118. [IF=1.5] Qian Xiaojing et al."Qualitative, Quantitative Analysis and Pharmacokinetic Study of Potentially Active Components of Huangxueyishen Decoction Based on UPLC-MS/MS."JOURNAL OF CHROMATOGRAPHIC SCIENCE.2025 Apr;63(4):
117. [IF=3.6] Sun Yilu et al."Six-compound combo remedy ameliorates corticosterone-induced depressive behaviors in mice via targeting HTR1A signaling."JOURNAL OF LEUKOCYTE BIOLOGY.2024 Jul;:
116. [IF=5.1] Jing-Qun Liu et al."Apigenin ameliorates lupus nephritis by inhibiting SAT3 signaling in CD8+T cells."Food & Function.2024 Sep;:
115. [IF=2.3] Li Can et al."Suppressing the virulence factors of Candida auris with baicalein through multifaceted mechanisms."ARCHIVES OF MICROBIOLOGY.2024 Aug;206(8):1-26
114. [IF=4.3] Hujun Du et al."Exploring the Underlying Mechanisms of Qingxing Granules Treating H1N1 Influenza Based on Network Pharmacology and Experimental Validation."Pharmaceuticals.2024 Jun;17(6):731
113. [IF=5.2] Qiuyan Jiang et al."Baicalein ameliorates lipid accumulation in HepG2 cells via the pregnane X receptor signaling pathway."Food Bioscience".2024 Aug;60:104482
112. [IF=5.4] Dan Yang et al."Study on the Effect of Pharmaceutical Excipient PEG400 on the Pharmacokinetics of Baicalin in Cells Based on MRP2, MRP3, and BCRP Efflux Transporters."Pharmaceutics".2024 Jun;16(6):731
111. [IF=5.6] Han Yu et al."Functional Identification of HhUGT74AG11—A Key Glycosyltransferase Involved in Biosynthesis of Oleanane-Type Saponins in Hedera helix."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES".2024 Jan;25(7):4067
110. [IF=5.4] Ruolan Sun et al."Homotherapy-for-heteropathy of Bupleurum Chinense DC.-Scutellaria baicalensis Georgi in treating depression and colorectal cancer: A network pharmacology and animal model approach."JOURNAL OF ETHNOPHARMACOLOGY".2024 Mar;:118038
109. [IF=6.6] Lingling Tang et al."Cleaner production of baicalein by novel high-temperature-little-acid hydrolysis of baicalin."Green Chemistry Letters and Reviews.10.1080/17518253.2024.2319698
108. [IF=7.9] Yanqin Luo et al."Scutellaria baicalensis water decoction ameliorates lower respiratory tract infection by modulating respiratory microbiota."PHYTOMEDICINE".2024 May;:155706
107. [IF=5.4] Botong Li et al."Protective effect of San Huang Pill and its bioactive compounds against ulcerative colitis in Drosophila via modulation of JAK/STAT, apoptosis, Toll, and Nrf2/Keap1 pathways."JOURNAL OF ETHNOPHARMACOLOGY.2024 Mar;322:117578
106. [IF=5.6] Lei Xie et al."Synthesis of Crocin I and Crocin II by Multigene Stacking in Nicotiana benthamiana."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.10.3390/ijms241814139
105. [IF=5.4] Wenqiang Yao et al."Tangzhiqing decoction attenuates cognitive dysfunction of mice with type 2 diabetes by regulating AMPK/mTOR autophagy signaling pathway."JOURNAL OF ETHNOPHARMACOLOGY.2024 Mar;321:117536
104. [IF=2.8] Qingmei Gong et al."Baicalein promotes the microglia M2 polarization and suppresses apoptosis by targeting HMOX1/PDE4D to alleviate Alzheimer’s disease."IMMUNOBIOLOGY.2023 Nov;:152761
103. [IF=6] Zeru Xu et al."Targeted screening of baicalein inhibitor with controlling lipid and protein oxidation for quality preservation of grass carp fillets."LWT-FOOD SCIENCE AND TECHNOLOGY.2023 Nov;:115526
102. [IF=4.3] Bao-Fei Yan et al."Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NF-κB pathway."WORLD JOURNAL OF GASTROENTEROLOGY.2023 Aug 21; 29(31): 4744–4762
101. [IF=1.7] Zhouyi Zhang et al."Revealing the differences in phenolics in different parts of Taraxacum mongolicum using UPLC-MS/MS."Phytochemistry Letters.2023 Aug;56:13
100. [IF=5.1] Meiling Yu et al."Baicalein ameliorates polymyxin B-induced acute renal injury by inhibiting ferroptosis via regulation of SIRT1/p53 acetylation."CHEMICO-BIOLOGICAL INTERACTIONS.2023 Sep;382:110607
99. [IF=5.2] Guo Huanyu et al."The combined effect of a novel formula of herbal extracts on bacterial infection and immune response in Micropterus salmoides."Frontiers in Microbiology.2023 Jun;14:
98. [IF=5.4] Miaomiao Liu et al."Qingjin Huatan decoction protects mice against influenza a virus pneumonia via the chemokine signaling pathways."JOURNAL OF ETHNOPHARMACOLOGY.2023 Dec;317:116745
97. [IF=1.967] ke Zunli et al."Physicochemical characteristics, polyphenols and antioxidant activities of Dimocarpus longan grown in different geographical locations."ANALYTICAL SCIENCES.2023 Apr;:1-8
96. [IF=3.842] Qiao Yinggu et al."Boldine promotes stemness of human urine-derived stem cells by activating the Wnt/β-catenin signaling pathway."MOLECULAR AND CELLULAR BIOCHEMISTRY.2023 Apr;:1-12
95. [IF=6.656] Siqi Liu et al."Screening quality makers (Q-makers) of Xiaoer Chaige Tuire Oral Liquid by in vitro sequential metabolism and in vivo biopharmaceutical analysis."PHYTOMEDICINE.2023 Apr;:154844
94. [IF=12.779] Haiyu Xu et al."Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19."PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.2023 Apr;120(18):e2301775120
93. [IF=1.555] Huang Zhen et al."Screening Antibacterial Constituents of Scutellaria Radix Based on Spectrum–Effect Relationships Between HPLC Fingerprints and the Inhibition of Oral Bacteria."JOURNAL OF CHROMATOGRAPHIC SCIENCE.2023 Mar;:
92. [IF=1.467] Wen-Xia Pi et al."Simultaneous quantification of multiple active components of the ginkgo ketoester tablet when combined with donepezil in four biological matrices from an Alzheimer’s animal model: Evaluation of drug distribution patterns in vivo."JOURNA
91. [IF=3.682] Yujia Liu et al."Dual-responsive antibiotic and baicalein co-delivery nanoparticles with enhanced synergistic antibacterial activity."JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION.
90. [IF=6.208] Na Li et al."STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2023 Jan;24(3):2987
89. [IF=2.586] Jiaxin Yin et al."Comprehensive multicomponent characterization and quality assessment of Shuang-Huang-Lian powder injection using ultra-high-performance liquid chromatography-quadrupole time-of-flight-mass spectrometry and ultra-high-performance liquid c
88. [IF=4.831] Jing Sun et al."Fourier transform infrared spectroscopic markers of the scorching degree of Scutellariae Radix related to the variation patterns of flavonoids and carbohydrates."SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY.2023 Apr;2
87. [IF=3.318] Hui Luo et al."Efficacy identification and active compounds screening of topically administration of Scutellaria Radix in oral ulcer."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES.2022 Dec;:123571
86. [IF=5.195] Bao-Fei Yan et al."Huangqin decoction mitigates hepatic inflammation in high-fat diet-challenged rats by inhibiting TLR4/NF-κB/NLRP3 pathway."JOURNAL OF ETHNOPHARMACOLOGY.2023 Mar;303:115999
85. [IF=5.195] Shou-Jia Wang et al."Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation."JOURNAL OF ETHNOPHARMACOLOGY.2023 Mar;303:116053
84. [IF=7.291] Liu Xiaojuan et al."Genome-wide analysis of cytochrome P450 genes in Citrus clementina and characterization of a CYP gene encoding flavonoid 3'-hydroxylase."Horticulture Research.2022 Dec;:
83. [IF=8.431] Dan Huang et al."Scavenging of reactive oxygen species effectively reduces Pseudomonas aeruginosa biofilms through disrupting policing."ENVIRONMENTAL RESEARCH.2023 Mar;220:115182
82. [IF=5.195] Xiaojing Wang et al."Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice."JOURNAL OF ETHNOPHARMACOLOGY.2022 Nov;:115919
81. [IF=6.269] Mengyu Cai et al."Nutritional supplements formulated to prevent cognitive impairment in animals."Current Research in Food Science.2022 Jan;5:2294
80. [IF=5.195] Weicong Chen et al."Biejiajian pill inhibits progression of hepatocellular carcinoma by downregulating PDGFRβ signaling in cancer-associated fibroblasts."JOURNAL OF ETHNOPHARMACOLOGY.2022 Oct;:115825
79. [IF=5.195] Zhen Huang et al."Efficacy confirmation of Scutellaria baicalensis Georgi in the treatment of periodontitis via topical administration and active ingredients screening."JOURNAL OF ETHNOPHARMACOLOGY.2023 Jan;300:115699
78. [IF=5.195] Xin Deng et al."A novel strategy for active compound efficacy status identification in multi-tropism Chinese herbal medicine (Scutellaria baicalensis Georgi) based on multi-indexes spectrum-effect gray correlation analysis."JOURNAL OF ETHNOPHARMACOLOGY.20
77. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747
76. [IF=7.419] Yule Wang et al."Discovery of anti-stroke active substances in Guhong injection based on multi-phenotypic screening of zebrafish."BIOMEDICINE & PHARMACOTHERAPY.2022 Nov;155:113744
75. [IF=6.212] Fei Huang et al."Discovery of conversion driven by β-glucuronidase from flavone glycoside to aglycone and application in identifying the raw Scutellariae Radix."Arabian Journal of Chemistry.2022 Aug;:104216
74. [IF=8.025] Ying Wang et al."Inhibitory activities of flavonoids from Scutellaria baicalensis Georgi on amyloid aggregation related to type 2 diabetes and the possible structural requirements for polyphenol in inhibiting the nucleation phase of hIAPP aggregation."INT
73. [IF=9.473] Yujing Wang et al."Scutellarein Attenuates Atopic Dermatitis by Selectively Inhibiting Transient Receptor Potential Vanilloid 3."BRITISH JOURNAL OF PHARMACOLOGY
72. [IF=6.576] Junkun Pan et al."Inhibition of Dipeptidyl Peptidase-4 by Flavonoids: Structure–Activity Relationship, Kinetics and Interaction Mechanism."Frontiers in Nutrition. 2022; 9: 892426
71. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155
70. [IF=5.811]
69. [IF=3.935] Yizhu Wang et al."Effects of Scutellaria baicalensis Georgi. on Intestinal Flora in Rats with Spleen Deficiency and Damp-heat."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2022 May;:114831
68. [IF=4.412] Jingjing Liao et al."Heterologous Biosynthesis of Health-Promoting Baicalein in Lycopersicon esculentum."MOLECULES. 2022 Jan;27(10):3086
67. [IF=4.821] Tian Quan et al."Effective extraction methods based on hydrophobic deep eutectic solvent coupled with functional molecularly imprinted polymers: Application on quercetagetin extraction from natural medicine and blood."Microchem J. 2022 Mar;174:107076
66. [IF=6.529] Fanying Meng et al."Virtual screening and in vitro experimental verification of LuxS inhibitors from natural products for Lactobacillus reuteri."Biomed Pharmacother. 2022 Mar;147:112521
65. [IF=7.514] Jinmiao Sun et al."Chitosan binding to a novel alfalfa phytoferritin nanocage loaded with baicalein: Simulated digestion and absorption evaluation."Food Chem. 2022 Aug;386:132716
64. [IF=3.41] Zhi-dan Gao et al."Mechanistic insights into the amelioration effects of lipopolysaccharide-induced acute lung injury by baicalein: An integrated systems pharmacology study and experimental validation."Pulm Pharmacol Ther. 2022 Mar;:102121
63. [IF=2.193] Zhang Haibo et al.Systematic Study on a Quantitative Analysis of Multicomponents by Single Marker (QAMS) Method for Simultaneous Determination of Eight Constituents in Pneumonia Mixture by UPLC-MS/MS.J Anal Methods Chem. 2021;2021:8311588
62. [IF=4.36] Jiali Zhou et al.The root extract of Scutellaria baicalensis Georgi promotes β cell function and protects from apoptosis by inducing autophagy.J Ethnopharmacol. 2022 Feb;284:114790
61. [IF=2.877] Wanli Ji et al."Identifying the active compounds and mechanism of action of Banxia Xiexin decoction for treating ethanol-induced chronic gastritis using network pharmacology combined with UPLC–LTQ–Orbitrap MS."Comput Biol Chem. 2021 Aug;93:107535
60. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950
59. [IF=3.004] Chun Chen et al."Comparative two-dimensional GPC3 overexpressing SK-Hep1 cell membrane chromatography /C18/ time-of-flight mass spectrometry for screening selective GPC3 inhibitor components from Scutellariae Radix."J Chromatogr B. 2021 Jan;1163:122492
58. [IF=3.263] Zongchun Yang et al."Baicalein improves glucose metabolism in insulin resistant HepG2 cells."Eur J Pharmacol. 2019 Jul;854:187
57. [IF=3.361] Mengmeng Yuan et al."The interaction of dietary flavonoids with xanthine oxidase in vitro: molecular property-binding affinity relationship aspects."Rsc Adv. 2019 Apr;9(19):10781-10788
56. [IF=3.935] Meng Chen et al."Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate."J Pharmaceut Biomed. 2021 Feb;195:113820
55. [IF=3.935] Chenglong Sun et al."A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi."J Pharmaceut Biomed. 2020 Feb;179:113014
54. [IF=4.35] Wanpei Tang et al."Phenolic Compounds Profile and Antioxidant Capacity of Pitahaya Fruit Peel from Two Red-Skinned Species (Hylocereus polyrhizus and Hylocereus undatus)."Foods. 2021 Jun;10(6):1183
53. [IF=4.759] Yi Zhang et al."Screening of inhibitors against histone demethylation jumonji domain-containing protein 3 by capillary electrophoresis."J Chromatogr A. 2020 Feb;1613:460625
52. [IF=4.759] Yueping Jiang et al."Application of multifold characteristic ion filtering combined with statistical analysis for comprehensive profiling of chemical constituents in anti-renal interstitial fibrosis I decoction by ultra-high performance liquid chromatogra
51. [IF=5.11] Xiaonan Liu et al."De Novo Biosynthesis of Multiple Pinocembrin Derivatives in Saccharomyces cerevisiae."Acs Synth Biol. 2020;9(11):3042–3051
50. [IF=5.279] Yanan Gao et al."Galactosylation of Monosaccharide Derivatives of Glycyrrhetinic Acid by UDP-Glycosyltransferase GmSGT2 from Glycine max."J Agr Food Chem. 2020;68(32):8580–8588
49. [IF=5.81] Mu Jianfei et al."Determination of Polyphenols in Ilex kudingcha and Insect Tea (Leaves Altered by Animals) by Ultra-high-performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry (UHPLC-QqQ-MS) and Comparison of Their Anti-Aging Effects."Fro
48. [IF=5.875] Guangjiao You et al."Preparation, optimization, characterization and in vitro release of baicalein-solubilizing glycyrrhizic acid nano-micelles."Int J Pharmaceut. 2021 May;601:120546
47. [IF=3.597] Jingying Qiu et al."Assessment of a bifendate derivative bearing a 6,7-dihydro-dibenzo[c,e]azepine scaffold as a potential anti-metastatic agent."Medchemcomm. 2018 Nov;9(11):1826-1830
46. [IF=3.738] Selma Houchi et al."Investigation of common chemical components and inhibitory effect on GES-type β-lactamase (GES22) in methanolic extracts of Algerian seaweeds."Microb Pathogenesis. 2019 Jan;126:56
45. [IF=3.935] Ka-Yan Kwok et al."Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography."J Pharmaceut Biomed. 2013 Nov;85:239
44. [IF=4.96] Liang Shi et al."Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC."Biochem Pharmacol. 2018 Apr;150:9
43. [IF=5.875] Qiuna Zhou et al."Baicalein and hydroxypropyl-γ-cyclodextrin complex in poloxamer thermal sensitive hydrogel for vaginal administration."Int J Pharmaceut. 2013 Sep;454:125
42. [IF=6.057] Jiantong Qiao et al."Sensitive determination of baicalein based on functionalized graphene loaded RuO2 nanoparticles modified glassy carbon electrode."Talanta. 2018 Oct;188:714
41. [IF=7.808] Jianhua Li et al."Production of plant-specific flavones baicalein and scutellarein in an engineered E. coli from available phenylalanine and tyrosine."Metab Eng. 2019 Mar;52:124
40. [IF=9.381] Qiuna Zhou et al."Preparation and characterization of inclusion complexes formed between baicalein and cyclodextrins."Carbohyd Polym. 2013 Jun;95:733
39. Chen, Meng, et al. "Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate." Journal of Pharmaceutical and Biomedical Analysis 195 (2021): 113820.https:##
38. Sun, Chenglong, et al. "A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi." Journal of pharmaceutical and biomedical analysis 179 (2020): 113014.https:##doi.org/10.1016/j.jpba.2019.11
37. Zhou, Qiuna, et al. "Baicalein and hydroxypropyl-γ-cyclodextrin complex in poloxamer thermal sensitive hydrogel for vaginal administration." International journal of pharmaceutics 454.1 (2013): 125-134.https:##doi.org/10.1016/j.ijpharm.2013.07.006
36. Cheng, Yan, et al. "Controlled Extraction of Flavonoids From Radix Scutellariae by Subcritical Water." CLEAN–Soil, Air, Water 44.3 (2016): 299-303.https:##doi.org/10.1002/clen.201300193
35. Qiu, Jingying, et al. "Assessment of a bifendate derivative bearing a 6, 7-dihydro-dibenzo [c, e] azepine scaffold as a potential anti-metastatic agent." MedChemComm 9.11 (2018): 1826-1830.https:##doi.org/10.1039/C8MD00294K
34. Xin-Guo Z, Kou F, Guo-Di M, Tang P, Zhong-Duo Y. Pharmacokinetics and pharmacodynamics of a novel Acetylcholinesterase Inhibitor, DMNG-3. Acta Neurobiologiae Experimentalis. 2016 ;76(2):117-124. DOI: 10.21307/ane-2017-011. PMID: 27373949.
33. Yang, Zongchun, et al. "Baicalein improves glucose metabolism in insulin resistant HepG2 cells." European journal of pharmacology 854 (2019): 187-193.https:##doi.org/10.1016/j.ejphar.2019.04.005
32. Tang W, Li W, Yang Y, Lin X, Wang L, Li C, Yang R. Phenolic Compounds Profile and Antioxidant Capacity of Pitahaya Fruit Peel from Two Red-Skinned Species (Hylocereus polyrhizus and Hylocereus undatus). Foods. 2021; 10(6):1183. https:##doi.org/10.3390/food
31. Shi, Liang, et al. "Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC." Biochemical pharmacology 150 (2018): 9-23.https:##doi.org/10.1016/j.bcp.2018.01.026
30. 紀萬里,周澤華,王婷婷,安叡,梁琨,王新宏.基于UPLC-LTQ-Orbitrap-MS方法分析半夏瀉心湯化學成分[J].藥物分析雜志,2020,40(10):1736-1750.
29. 馬宗敏,苗文麗,劉佳,何培,孫國強,裴林.黃芩內(nèi)生真菌發(fā)酵黃芩苷生成千層紙素A的代謝途徑及轉(zhuǎn)化條件研究[J].天然產(chǎn)物研究與開發(fā),2020,32(11):1928-1936.
28. 沈亮亮,李勇,周明,譙英固,孫震曉.增強人尿源性干細胞干性的中藥小分子活性成分篩選[J].中國新藥雜志,2020,29(24):2839-2845.
27. 李壯壯, 張靜, 趙紹哲,等. 指紋圖譜與化學計量學結(jié)合優(yōu)選柴胡桂枝顆粒水提工藝[J]. 中成藥, 2018, v.40(08):199-203.
26. 范琳琳, 王英, 黃自蘇,等. 外源添加物質(zhì)對黑莓清汁花色苷穩(wěn)定性和抗氧化活性的影響[J]. 食品工業(yè)科技, 2019, v.40;No.420(04):62-67.
25. 楊夢玲, 尤朋濤, 何麗珊,等. 基于UPLC-MS/MS分析胃潰瘍模型大鼠口服加味小柴胡顆粒后血漿中8種有效成分的藥代動力學[J]. 中國中藥雜志, 2018, 43(18).
24. 陳智. 金銀花和黃芩不同煎煮方式化學成分變化及抗病毒作用比較[J]. 中華中醫(yī)藥雜志, 2019, v.34(10):129-133.
23. 任永申, 鄧鑫, 雷蕾,等. 基于抑菌效應成分指紋譜的黃芩質(zhì)量評價研究[J]. 藥學學報, 2019, 054(012):2155-2161.
22. 李云靜, 張建逵, 趙玥,等. 黃芩藥材顏色及其有效成分的相關(guān)性[J]. 中國醫(yī)藥工業(yè)雜志, 2017(7).
21. 馬宗敏, 劉佳, 段緒紅,等. 黃芩苷發(fā)酵轉(zhuǎn)化成黃芩素和千層紙素A的黃芩內(nèi)生真菌的篩選及鑒定[J]. 中國實驗方劑學雜志, 2019(9):166-171.
20. 吳逸晨, 謝輝, 毛春芹,等. 復方甘草清瘍合劑HPLC指紋圖譜[J]. 中成藥, 2019, 041(009):2251-2256.
19. 袁杰, 李錟, 周利,等. 基于超高效液相色譜法和色差儀法的黃芩藥材質(zhì)量評價[J]. 世界中醫(yī)藥, 2019.
18. 柴沖沖,曹妍,毛民,王靖越,劉娜,李欣欣,張凱,陳東玲,魏龍吟,尹怡慧,李飛.基于電子舌技術(shù)評價黃芩酒炙前后滋味變化及其在黃芩飲片鑒別中的應用研究[J].中國中藥雜志,2020,45(11):2552-2559.
17. 張慧, 李思雨, 馮宏玲,等. 基于效應成分指數(shù)的雙黃連制劑質(zhì)量控制研究[J]. 藥學學報, 2019, 054(012):2149-2154.
16. 柴沖沖 毛民 袁金鳳 等. 不同方法軟化切制后的黃芩飲片顏色與5種黃酮類成分含量的相關(guān)性研究[J]. 中國中藥雜志 2019.
15. 郭凈潔, 王崇, 張維甲,等. 黃芩素與黃芩苷聯(lián)合用藥對口腔鱗癌細胞增殖,遷移的影響[J]. 口腔醫(yī)學, 2020, 040(005):393-398.
14. 程燕, 曲紹風, 李福偉,等. 黃芩中4種黃酮類化合物的亞臨界水提取研究[J]. 山東科學, 2013(03):11-14.
13. 劉媛媛, 劉陶, 吳玉梅,等. 基于雌激素受體調(diào)節(jié)Nrf2-ARE通路的黃芩中抗氧化成分的篩選[J]. 中國藥理學通報, 2019, 035(006):822-827.
12. 商利娜, 王亞靜, 趙鑫,等. 基于譜-效關(guān)系探究黃芩抑制白色念珠菌的質(zhì)量標志物[J]. 中成藥, 2020, 042(005):1357-1361.
11. 李淑嬌, 王宇卿. 基于HPLC-Q-TOF/MS法的黃芩血清藥物化學分析[J]. 中成藥, 2019, 41(03):117-122.
10. 陳慧潔 楊亞楠 丁輝 等. 養(yǎng)陰利咽半生制劑袋泡茶的制備及優(yōu)化[J]. 天津中醫(yī)藥大學學報 2019 38(01):78-83.
9. 王東超 魏穎 高佳琪 孫文 秦靈靈 蘭衛(wèi) 石浩霞 李博 徐暾海 劉銅華.HPLC同時測定糖痹康顆粒中黃芩苷、漢黃芩苷、黃芩素、漢黃芩素的含量[J].吉林中醫(yī)藥 2017 37(05):513-517.
8. 王健, 李健, 王勇,等. 黃芩素通過抑制PI3K/AKT/mTOR 通路誘導膀胱癌細胞凋亡[J]. 山東大學學報(醫(yī)學版), 2019(9).
7. 溫紹霞, 武軍駐. 黃芩素對肺炎克雷伯菌生長及生物膜形成能力影響的研究[J]. 檢驗醫(yī)學與臨床, 2013(20):2707-2708.
6. 張瀛, 皮佳鑫, 李雯,等. 黃芩素-茶堿共晶的溶劑體系篩選及體外溶出度評價[J]. 天津中醫(yī)藥, 2020, v.37(01):98-103.
5. 周秋娜, 尉小慧, 王崢濤. 黃芩素-羥丙基-γ-環(huán)糊精包合物制備工藝研究[J]. 上海中醫(yī)藥雜志, 2013, 047(008):82-85.
4. 陳智, 田景振. 基于模擬炮制法研究黃芩炒炭前后苷類成分的變化[J]. 山東中醫(yī)藥大學學報, 2020, v.44;No.242(01):85-90.
3. 岑建斌 梁志森 區(qū)碩俊 黃嘉樂 李秀英 林青蘭 陳玉珍 劉炘杰 林森煜.分散固相萃取-高效液相色譜-串聯(lián)質(zhì)譜法同時測定保健品片劑中5種黃芩素類化合物[J].色譜 2020 38(06):672-678.
2. 李云靜 張建逵 王冰 等. 不同產(chǎn)地黃芩藥材中黃芩苷等5種黃酮類成分含量的比較[J]. 時珍國醫(yī)國藥 2016 027(012):2985-2988.
1. 馬宗敏 苗文麗 段緒紅 等. 一株發(fā)酵轉(zhuǎn)化黃芩苷菌株的篩選及鑒定[J]. 天然產(chǎn)物研究與開發(fā) 2019 31(02):49-54.
